DSIP was first isolated by Schoenenberger and Monnier at the University of Basel in the 1970s during cross-circulation studies in rabbits, where blood from sleeping animals appeared to contain a sleep-promoting factor
-Wharton S, Blevins T, Connery L, et al
Uncommon Side Effects (Affecting 2-10% of Users) Abdominal pain, dizziness, acid reflux, low blood sugar in diabetics on other medications, mild heart rate increase, and temporary hair thinning all fall into this category
Nine residues is long enough to be a comfortable substrate for endopeptidases as well as exopeptidases, so in serum-containing medium over a long incubation the concentration falls
Additionally, protecting your eyes from sun damage with UV-protective sunglasses is vital
The 200mg dose is designed to deliver comparable blood levels to 500-1,000mg of standard berberine